She Gan (Rhizoma Belamcanda)

What Is She Gan

She Gan commonly known as Rhizoma Belamcanda is the rhizome of Belamcanda chinensis, which is a perennial herb belonging to the family Iridaceae. It first appeared in <Shennong Ben Cao Jing> in the late Western Han Dynasty (around 100 BCE).

Belamcanda chinensis is also known as Leopard lily, Blackberry lily, or Leopard flower, and is an ornamental plant. In 2005, based on evidence from the molecular DNA sequence, it was renamed Iris domestica. But the old name is still in general use.

This plant is cold-resistant and drought-tolerant. It often grows on forest edges or hillside grasslands at low altitudes. They are native to East Asia and have been widely introduced and cultivated. It is now mainly distributed in temperate and subtropical regions. In many places, it has escaped from cultivation, particularly in the USA.

Belamcanda chinensis

In addition, It is also commonly used in traditional medicine in India, Korea, and Japan. Recently, a monograph of Belamcandae chinensis rhizoma has been included in the European Pharmacopeia.

In the early spring and late autumn of each year, people gather the rhizomes of Belamcanda chinensis, wash them with water, remove their impurities and fibrous roots, moisten them thoroughly, cut them into slices, dry them in the sun, and make them into Chinese herbal medicines.

She Gan contains belamcandin, tectoridin, iridin, tectorigenin, tectorigenin A, irigenin, tectorigenin B, irisflorentin, dichotomitin, mangiferin, bicyclic triterpenes, and phenols.

Generally, solid She Gan with a yellowish cross-section is preferred.

According to the Chinese Pharmacopoeia, the medicinal nature of She Gan is relatively cold, with a bitter taste. It has a certain therapeutic effect on the pathological changes of the lung meridian.

In traditional Chinese medicine, She Gan is often used to clear heat and remove toxins, eliminate phlegm and relieve sore throat, treat bronchitis, asthma, pneumonia, pharyngitis, chronic sinusitis, chyluria, impotence, and paddy-field dermatitis.

About 50 kinds of traditional Chinese medicine prescriptions contain it, such as Bie Jia Jian Wan, Shegan-Mahuang Decoction, and Watermelon Frost Spray.


  • Anti-inflammation, anti-allergen, and anti-tumor.
  • Anti-oxidation, scavenging H2O2, hydroxyl radical, and superoxide anion.
  • Inhibiting influenza virus, adenovirus, Echovirus, Coxsackie virus, herpes virus.
  • Inhibiting platelet aggregation and preventing thrombosis.
  • Reducing the damage of CCL4 to liver tissue and protecting the liver.
  • Inducing diuresis and having antipyretic and analgesic effects.
  • Lowering hyperglycemia and high serum total cholesterol, triglycerides, low-density lipoprotein, and very-low-density lipoprotein-cholesterol, preventing diabetes and concurrent certificate.
  • Promoting saliva and bile secretion, and inhibiting gastric ulcers, and small intestinal diarrhea caused by castor oil.
  • Removing heat toxins, relieving throat swelling and pain caused by heat toxins or the coagulation of phlegm-fire.
  • Dispelling wind and heat, relieving sore throat and hoarse voice caused by wind-heat.
  • Eliminating yellow phlegm, and relieving cough and wheezing caused by lung heat.
  • Eliminating white thin phlegm and treating cough and wheezing due to lung plugged by cold phlegm.
  • Inhibiting Staphylococcus aureus, Streptococcus A, Streptococcus B, Pneumococcus, Meningococcus, Escherichia coli, Typhoid, Paratyphoid, Haemophilus influenzae, and Helicobacter pylori.
  • Inhibiting pathogenic superficial fungi, such as Trichophyton rubrum, trichophyton gypseum, Microsporum lanosum, Epidermophyton floccosum, Microsporum gypseum, Trichophyton tonsurans, Trichophyton violaceum, Trichophyton mentagrophytes, and Microsporium canis.
  • It contains phytoestrogens, which can inhibit the proliferation of prostate cancer cells, but it does not promote the proliferation of the uterus and breasts.


Side Effects

  • Clinically, there have been reports of diarrhea caused by taking She Gan, but there is no report of poisoning after taking it.
  • A small proportion of patients taking it may cause loss of appetite, nausea, vomiting, diarrhea, or watery stools.

Precautions and Warnings

  • The dosage of She Gan should be controlled at 3-9g.
  • It can be made into decoctions, pills, or ground into powder for external use.
  • People who are allergic to She Gan should not take it.
  • Patients with loose stools caused by spleen deficiency should not take it.
  • Patients with a deficiency of both qi and blood should not take it.
  • Patients with no syndromes of excess heat should not take it.
  • Pregnant women and children should not take it.