Bu Zhong Yi Qi Wan (Bu Zhong Yi Qi Tang or Bu Zhong Yi Qi Pian)

What Is Bu Zhong Yi Qi Wan

Bu Zhong Yi Qi Wan is a classic and famous Chinese medicine prescription. It first appeared in <Pi Wei Lun> (Treatise on the Spleen and Stomach) in the Jin and Yuan Dynasties (about 1249AD).

Bu Zhong means “strengthen the middle-jiao”, Yi Qi means “benefit qi”, and Wan means “edible pills”. It is a commonly used Chinese patent medicine for the treatment of spleen and stomach dysfunction.

In traditional Chinese medicine, it is often used to invigorate the middle-Jiao and qi, ascend up spleen-qi and yang, recurrent oral ulcer, fever due to qi deficiency, puerperal high fever, children with recurrent respiratory tract infection, chronic rhinitis, chronic hepatitis, overstrain strangury, myasthenia gravis, chyluria, splanchnoptosis, gastroptosis, prolapse of the uterus, archoptosis, chronic diarrhea, postpartum dysuria, pregnancy dysuria, fetal irritability, menorrhagia, ptosis, paralytic strabismus, and primary azoospermia.

In the early days, this prescription was called Bu Zhong Yi Qi Tang, which was a decoction. It is improved into pills for ease of taking and saving medicinal herbs.

With the development of pharmaceutical technology, it has been improved into pills, granules, and oral liquids with a more standardized dosage.

In the market, the common Bu Zhong Yi Qi Wan include Bu Zhong Yi Qi Wan, Bu Zhong Yi Qi Pian, Bu Zhong Yi Qi Oral Liquid, and Buzhong Yiqi Granules.

Ingredients

The dosage of Huang Qi is the largest in this prescription. Its medicinal nature is relatively warm. It can invigorate the spleen and strengthen the middle jiao, ascend up spleen-qi and yang.

The medicinal nature of Dang Shen is relatively neutral. It can invigorate the spleen and benefit the lung. It synergizes with Huang Qi to help invigorate the spleen and benefit the lung, relieve cough and asthma.

The medicinal nature of Bai Zhu is relatively warm. It can invigorate the spleen and replenish qi, dry dampness. It synergizes with Huang Qi to help recuperate middle-qi.

The medicinal nature of Dang Gui is relatively warm. It can nourish blood and activate blood. It synergizes with Huang Qi and Dang Shen to help benefit qi and nourish the blood.

The medicinal nature of Chen Pi is relatively warm. It can regulate qi and invigorate the spleen, regulate the stomach. It can be used in combination with Dang Shen and Bai Zhu to treat qi stagnation due to spleen deficiency.

The medicinal nature of Sheng Ma is slightly cold. It can elevate yang. The medicinal nature of Chai Hu is slightly cold. It can send up the lucid yang. They synergize with Huang Qi to help benefit qi and elevate yang.

The medicinal nature of Gan Cao is relatively neutral. It can invigorate the spleen and replenish qi. It can reconcile the effects of other Chinese herbal medicines in this prescription.

Benefits

  • Reducing the body temperature of rats with fever caused by spleen deficiency.
  • Improving T and B lymphocyte proliferation and NK cell activity in cyclophosphamide immunosuppressed mice.
  • Reducing bleomycin-induced lung injury in mice and alleviating pulmonary fibrosis in mice.
  • Reducing liver tissue malondialdehyde content, increasing liver glycogen content, improving liver oxidative metabolism, and liver oxidative damage.
  • Improving the concentration, quantity, density, and mobility of semen, and treating infertility with reduced sperm.
  • Inhibiting testosterone propionate-induced prostatic hyperplasia in rats.
  • Antagonizing the decrease in bone mass caused by cyclophosphamide and preventing osteoporosis.
  • Inhibiting gastric acid secretion, increasing gastric mucosal blood flow, and reducing gastric mucosal damage.
  • Inhibiting the proliferation of liver cancer Hep3B cells, HepG2 cells, and HA22T cells.
  • Treating diarrhea, loose stools, chronic diarrhea, dyspepsia, shortness of breath, muscle weakness, loss of appetite, abdominal distention, yellow complexion caused by weakness of the spleen and the stomach, or sinking of qi of middle-jiao.
  • Treating distending and bearing-down sensation in the abdomen, increased thin leucorrhea, fatigue, pale complexion, weakness of limbs, palpitation, shortness of breath, prolapse of the anus, and splanchnoptosis caused by deficiency of qi in middle-jiao, or collapse from qi deficiency.
  • Treating myasthenia gravis, chyluria, chronic hepatitis, prolapse of the uterus, postpartum dysuria, pregnancy dysuria, fetal irritability, menorrhagia, ptosis, and paralytic strabismus.
  • Studies have found that it can prolong the exhaustive swimming time of mice under normal pressure and hypoxia. It has an anti-fatigue effect.

How to use it

When using Bu Zhong Yi Qi Wan, follow the instructions for the medicine. Bu Zhong Yi Qi Wan include candied pills, water pills, tablets, and oral liquids.

When taking its candied pills, you should take it with warm water. The dosage per administration is about 9g. Take it 2-3 times a day.

When taking its water pills, you should take it with warm water. The dosage per administration is about 6g. Take it 2-3 times a day.

When taking its tablets, you should take it with warm water. The dosage per administration is 4-5 tablets (about 1.8-2.3g). Take it 3 times a day.

When taking its oral liquid, it should be taken directly. The dosage per administration is 10ml. Take it 2-3 times a day.

Generally, after taking the medicine for a week, the patient’s symptoms will be relieved. Patients should stop using it when their symptoms have resolved.

Side Effects

At present, no data have been found to show that there will be adverse reactions when it is taken in the prescribed dose.

Precautions and Warnings

  • During the medication, it is not recommended to eat indigestible foods.
  • People who are allergic to the ingredients in Bu Zhong Yi Qi Wan should not take it.
  • People with severe chronic diseases such as high blood pressure, heart disease, liver disease, diabetes, and kidney disease should take it under the guidance of a physician.
  • People with colds should not take it.
  • Patients with internal heat due to yin deficiency should not take it.
  • Pregnant women and breastfeeding women should take it under the guidance of a doctor.
  • Children, the elderly, and the infirm should take it under the guidance of a doctor.
  • After taking the medicine, if there is an adverse reaction, the patient should stop the medicine in time and go to the hospital for treatment.
  • If you are taking other drugs at the same time, you should consult your doctor to prevent interactions between the drugs and affect the efficacy of the drugs.
  • After 4 weeks of continuous medication, if the symptoms do not improve or the symptoms get worse, you should stop the medicine immediately and go to the hospital in time.